Why What Used to Work Doesn’t Work Anymore
Weight, metabolism and body composition after 35
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Wednesday, January 6, 2027 at 12pm ET · Free · 45 minutes
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Why What Used to Work Doesn’t Work Anymore
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Where would you start?
Every program is clinician-led. A licensed clinician decides what, if anything, is prescribed.
Medical Weight Loss
For weight that stopped responding to effort after 40.
- Clinician-led GLP-1 programs
- Semaglutide and tirzepatide options
- Base labs where indicated
Microdosing
Lower doses for energy, appetite and holding on to muscle.
- Semaglutide or tirzepatide
- Gentler ramp, same oversight
- One injection a week
Female Menopause - HRT
Hot flashes, sleep, mood and dryness, treated as one system.
- Estradiol and progesterone options
- Non-hormonal options too
- Clinician decides what fits
Longevity
Recovery, sleep and cellular energy for the long game.
- NAD+, B12-MIC, sermorelin
- Injection, nasal or oral options
- Clinician reviews every intake
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You may be eating the way you always have, exercising regularly, and wondering why maintaining your weight suddenly takes so much more effort.
The answer is rarely: try harder.
What you’ll learn
To move away from restriction and guilt, toward a strategy that supports fat loss, muscle, energy and long-term health.
Why it got harder, specifically: The actual physiological changes behind the shift, rather than the vague sense that your metabolism broke.
Muscle is the part nobody mentions: Why preserving muscle matters more than the number on the scale, and what happens to it in midlife if nothing intervenes.
Protein, fiber and blood sugar: The three things that move the needle most, in practical amounts rather than optimized-athlete amounts.
When medical options are worth discussing: An honest account of where GLP-1 medications fit, who they suit, and who they do not.
Who you’ll hear from
Named with credentials before the event. No actors, no influencers presented as clinicians, no AI personas.

Host, PureMuze Webinars
Questions about this webinar
The rest of the series
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Dec 2, 2026 at 12pm ETThis session is general health education, not medical advice, and attending does not create a clinician-patient relationship. Nothing said is a diagnosis or a treatment recommendation for you specifically. Compounded medications are not FDA-approved and are not reviewed by the FDA for safety, effectiveness or quality. Speak with your own clinician about your circumstances.